J Korean Ophthalmol Soc.  2021 Nov;62(11):1518-1526. 10.3341/jkos.2021.62.11.1518.

Symmetry of Peripapillary-Optical Coherence Tomography Angiography Parameters between Dominant and Non-dominant Eyes in Normal Eyes

• Ryu CK
• Lim HB
• Kim JY

• KMID: 2522329
• DOI: http://doi.org/10.3341/jkos.2021.62.11.1518

Abstract

Purpose
To assess whether optical coherence tomography (OCT) measurements and peripapillary microvascular parameters measured via optical coherence tomography angiography (OCTA) were similar between the dominant and non-dominant eyes of normal subjects.
Methods
We retrospectively analyzed spectral domain OCT and OCTA data on healthy Koreans. The “hole-in-the-card” technique was used to determine ocular dominance. The perfusion density (PD) and flux index (FI) of the peripapillary 4.5 × 4.5-mm area were measured via OCTA. Central macular, peripapillary retinal nerve fiber layer, and macular ganglion cell-inner plexiform layer thicknesses were measured with the aid of spectral-domain OCT. The OCT and OCTA data of dominant and non-dominant eyes were compared.
Results
A total of 84 eyes of 42 healthy subjects were analyzed. The average age was 27.3 ± 5.63 years. Twenty-eight subjects (66.7%) were right eye-dominant and 14 (33.3%) left eye-dominant. None of the central macular (260.00 ± 14.16 μm, 258.71 ± 15.18 μm, p = 0.183), macular ganglion cell-inner plexiform layer (82.02 ± 5.07 μm, 82.43 ± 5.60 μm, p = 0.460), or peripapillary retinal nerve fiber layer thickness (99.36 ± 9.27 μm, 97.90 ± 9.46 μm, p = 0.091) differed between the eyes; neither did any OCTA-assessed microvascular parameter.
Conclusions
No OCT or OCTA parameter differed between dominant and non-dominant eyes. No parameter identified ocular dominance.

Keyword

Ocular dominance, Optical coherence tomography angiography, Peripapillary perfusion density