J Korean Ophthalmol Soc.  2020 Sep;61(9):1057-1064. 10.3341/jkos.2020.61.9.1057.

Symmetry of Optical Coherence Tomography Angiography Parameters between Dominant and Non-dominant Eyes in Healthy Koreans

• Kim KM
• Lim HB
• Shin YI
• Jo YJ
• Kim JY

• KMID: 2506480
• DOI: http://doi.org/10.3341/jkos.2020.61.9.1057

Abstract

Purpose
To assess the symmetry of microvascular parameters measured via optical coherence tomography angiography (OCTA) between the dominant and non-dominant eyes of normal Korean subjects.
Methods
We retrospectively analyzed data on 120 eyes of 60 healthy Koreans. The ‘hole-in-the-card’ technique was used to determine ocular dominance. Central macular, peripapillary retinal nerve fiber layer thickness, and macular ganglion cell-inner plexiform layer thickness, were measured via spectral domain OCT. Vessel and perfusion density and the area of the foveal avascular zone (FAZ) were measured via OCTA. We used the paired t-test to compare all between-eye parameters. We calculated areas under receiver operating characteristic curves to determine diagnostic utility.
Results
The average participant age was 27.4 ± 2.01 years. Forty-one subjects (68.3%) were right eye-dominant and 19 (31.7%) left eye-dominant. None of the central macular, macular GC-IPL, or peripapillary RNFL thickness differed between the eyes; neither did any OCTA-assessed microvascular parameter (vessel or perfusion density or the FAZ area).
Conclusions
No OCT or OCTA parameter differed between dominant and non-dominant eyes. No parameter identified ocular dominance.

Keyword

Ocular dominance; Optical coherence tomography angiography; Vascular density