Korean J Transplant.  2021 Oct;35(Supple 1):S66. 10.4285/ATW2021.PO-1135.

Incidental renal cell carcinoma in a native kidney of patient with autosomal dominant polycystic kidney disease for renal transplantation: a case report

• Shin BC
• Shin MH
• Kim HL
• Chung JH
• Choi NG

• KMID: 2521410
• DOI: http://doi.org/10.4285/ATW2021.PO-1135

Abstract

Background
Autosomal dominant polycystic kidney disease (ADPKD) is an important cause of end-stage renal disease. Pretransplant native nephrectomy is performed to create space in the pelvis, to decrease compression by the enlarged polycystic kidney, and to prevent development of various symptoms.
Case report
A 63-year-old male with end-stage kidney disease due to ADPKD planned to deceased donor kidney transplantation. Because of massive enlarged kidneys, he underwent a bilateral nephrectomy. The diameter of the right kidney was 22×17 cm and left kidney 22×16 cm. Pathology indicated multifocal renal cell carcinoma in both kidney with Fuhrman nuclear grade 3/4 and no lymphovascular invasion.
Conclusions
This case reinforces the importance of considering the possibility of an occult malignancy in the native kidneys of patients with ADPKD. we present a case of incidental renal cell carcinoma in a patient with ADPKD who underwent bilateral native nephrectomy for deceased donor renal transplantation.