J Korean Soc Transplant.  2014 Dec;28(4):246-249. 10.4285/jkstn.2014.28.4.246.

Papillary Adenoma Identified in Removed Polycystic Kidneys during Kidney Transplantation in Autosomal Dominant Polycystic Kidney Disease Patient

• Chai MH
• Park H
• Kim Y
• Kim JS
• Kim SH
• Eom M
• Yang JW
• Han BG
• Choi SO

• KMID: 1941321
• DOI: http://doi.org/10.4285/jkstn.2014.28.4.246

Abstract

Kidney transplantation is the preferred treatment in end stage renal disease for autosomal dominant polycystic kidney disease (ADPKD) patients. Removal of the native kidney is not usually recommended for ADPKD patients during a transplantation procedure because the operation time may be prolonged or the risk of bleeding may be higher. Therefore, native kidney removal is indicated for patients with chronic pain by enlarged kidney, frequent complications from cysts, such as infection or bleeding, and renal tumor development. Here, we report a case of a patient whose native kidneys were removed during a kidney transplantation procedure, and multifocal adenomas were identified in the removed kidneys after the procedure.

Keyword

Autosomal dominant polycytic kidney; Adenoma; Kidney transplantation

MeSH Terms

Adenoma*
Chronic Pain
Hemorrhage
Humans
Kidney
Kidney Failure, Chronic
Kidney Transplantation*
Polycystic Kidney Diseases*
Polycystic Kidney, Autosomal Dominant*

Figure

• 

  Fig. 1. Gross appearance of polycystic kidney removed from recipient during kidney transplant procedure. The surface and internal part of polycystic kidney are composed of numerous cysts of variable sizes.

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  Fig. 2. Pathologic findings in the parenchyma of polycystic kidney. (A∼ C) Light microscopy shows papillary proliferation of bland epithelial cells (HE stain, ×200). (D) Immunohistochemical stain for cytokeratin-7 is positive in the cytoplasm of tumor cells (×200).

Reference

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