Korean J Transplant.  2021 Oct;35(Supple 1):S26. 10.4285/ATW2021.OP-1216.

Evaluating heart transplantation outcomes from marginal donors

• Naseri AS
• Shakerian B
• Bagherpour F
• Ashraf H
• Karbalai S
• Soleimani A
• Rezai A
• Hamidieh A
• Latifi M

• KMID: 2521237
• DOI: http://doi.org/10.4285/ATW2021.OP-1216

Abstract

Background
Considering lack of enough resources, such as artificial heart or ventricular assist devices for long term cardiac replacement therapy, we decided to evaluate those brain death cases, which seem non eligible as heart donor based on guidelines criteria, as marginal donners, but with no contraindication for replacement at preoperational evaluation.
Methods
This retrospective study was conducted on heart donors and their recipients at Organ Procurement Unit of Sina. Among the candidates, 75 were categorized as standard donors (group A) and 18 were marginal donors (group B), group C were heart recipients from standard donors, and group D were heart recipients from marginal donors.
Results
Based on this study 97 heart donors of a total number of 302 donors referred to Sina Hospital, 80.6% were sub grouped as group A, standard donor, and 19.4% group B as marginal group (older than 40 years, or with positive history of drug abuse or smoking, but based on echocardiography and coronary angiography, negative for HIV, or hepatitis infection). Their mean survival rate in groups C and D were 635.67±434.75 and 508.46±407.8 days respectively with no significant difference between survival rates in MD and SD recipients (P=0.961).
Conclusions
Based on this study, marginal donors could be eligible for harvesting, and decrease wait time for end stage heart recipients.