Nat Prod Sci.
2021 Sep;27(3):172-175. 10.20307/nps.2021.27.3.172.
Sesbagrandiflorain F, a New 2-Arylbenzofuran from the Stem Bark of Sesbania grandiflora L.
- Affiliations
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- 1Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya, Indonesia
- 2Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Surabaya, Surabaya, Indonesia
- KMID: 2521086
- DOI: http://doi.org/10.20307/nps.2021.27.3.172
Abstract
- Sesbagrandiflorain F (1), a novel 2-arylbenzofuran, and two more 2-arylbenzofurans (2-3), were isolated from the stem bark of Sesbania grandiflora L. Based on information HRESIMS data, 1D, and 2D NMR spectra, the structure of 1 was fully assigned. Compounds 1-3 were tested for cytotoxicity in MCF-7 and HeLacells. Compounds 1 and 3 showed moderate activity against MCF-7 cells with an IC50 value of 2.68 and 4.08 µg/mL,respectively. Conversely, all of the isolates were inactive towards HeLa cells.
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