J Korean Soc Radiol.  2021 Sep;82(5):1334-1340. 10.3348/jksr.2020.0193.

CT and MRI Features of Localized Peritumoral Amyloidosis in a Patient with Head and Neck MucosaAssociated Lymphoid Tissue Lymphoma: A Case Report

• Kim HJ
• Hong HS
• Kim JY

• KMID: 2520717
• DOI: http://doi.org/10.3348/jksr.2020.0193

Abstract

Amyloidosis has been reported to be associated with non-Hodgkin lymphoma. Amyloidosis and lymphoma can be related in two ways: lymphoma-associated systemic amyloidosis and peritumoral amyloidosis with lymphoma. We report a rare case of peritumoral amyloidosis in a patient with head and neck mucosa-associated lymphoid tissue lymphoma. On CT, the oropharyngeal mass showed an irregularly shaped soft-tissue density with multifocal amorphous calcifications and heterogeneous enhancement. On MRI, the mass showed heterogeneous low signal intensity on both T1- and T2-weighted images. On contrast-enhanced MR images, the mass showed good enhancement with several inner non-enhancing foci. Concurrent pathologies, such as peritumoral amyloidosis, should be considered when calcifications are noted in patients with pre-treatment lymphoma.

Keyword

Amyloidosis; Lymphoma; B-Cell; Marginal Zone; Computed Tomography; X-Ray; Magnetic Resonance Imaging