Korean Circ J.  2021 Oct;51(10):837-850. 10.4070/kcj.2021.0098.

Late Coronary Aneurysm Formation after Kawasaki Disease: a Review of Mechanistic and Clinical Aspects

Affiliations
  • 1Department of Cardiology, Trakya University, Edirne, Turkey
  • 2Department of Pathology, Trakya University, Edirne, Turkey
  • 3Department of Cardiology, Derindere Hospital, Istanbul, Turkey

Abstract

In patients with Kawasaki disease (KD), evolution of coronary artery aneurysms (CAAs) generally emerges within the first few weeks after disease onset. However, CAA formation in these patients might occasionally arise as a late-onset phenomenon after a long latent period. Characteristically, late CAAs manifest as new-onset vascular pathologies or expansion of long-stable CAAs on coronary imaging modalities, and might have diverse mechanistic and clinical implications. Accordingly, the present paper aims to focus on late CAA formation and its implications in the setting of KD.

Keyword

Kawasaki disease; Coronary artery; Aneurysm

Figure

  • Figure 1 Potential mechanisms of late CAA formation in the setting of KD.CAA = coronary artery aneurysm; KD = Kawasaki disease.*Generally presenting with mild and transient dilatation of coronary arteries.1)8)9)


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