Psychiatry Investig.  2021 Sep;18(9):831-840. 10.30773/pi.2021.0182.

Validation of Social Responsiveness Scale for Korean Preschool Children With Autism

Affiliations
  • 1Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea
  • 2Department of Psychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
  • 3Department of Psychiatry, Kyung Hee University Hospital, Seoul, Republic of Korea
  • 4Seoul National University College of Medicine, Seoul, Republic of Korea

Abstract


Objective
This cross-cultural study aims to examine the psychometric properties of the Social Responsiveness Scale (SRS) and to determine the best-estimate-cut-off scores for the diagnosis of autism spectrum disorder (ASD) in Korean preschool children.
Methods
A total of 563 children was recruited from multiple sources, including Seoul National University Bundang Hospital. Participants were assessed by a multidisciplinary research team using multiple diagnostic tools based on DSM-5 diagnostic criteria. Discriminative validity was tested by comparing the difference in SRS scores between ASD and non-ASD groups. Convergent validity was tested by examining correlations between SRS scores with other diagnostic instruments. A receiver operation characteristic curve analysis was conducted to test the sensitivity and specificity of SRS and to determine the best-estimate-cut-off scores for screening ASD in Korean preschool children.
Results
There were significant differences in the total SRS scores between the ASD (n=242) and non-ASD group (n=321) (p<0.01, 95% confidence interval [CI]: 14.08–17.24). The differences were significant even after adjusting for age. SRS scores were significantly correlated with other prescreening diagnostic tools for ASD. The best-estimate cut-off score to screen ASD was 55 (area under curve=0.88, sensitivity 78.1%, specificity 86.6%).
Conclusion
The SRS is a valid and reliable instrument to screen and aid in the diagnosis of ASD in Korean preschool children. The adjusted cut-off scores, notably lower than in the original U.S. version, may yield a more accurate diagnosis by reflecting transcultural differences.

Keyword

Autism spectrum disorder; Social Responsiveness Scale; Validation; SRS
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