J Korean Neurol Assoc.  2021 Aug;39(3):185-187. 10.17340/jkna.2021.3.12.

Targeted Temperature Management of Severe Lactic Acidosis in a Patient with MELAS Syndrome after Cardiac Arrest

Affiliations
  • 1Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea
  • 2Department of Neurology, Seoul National University Hospital, Seoul, Korea
  • 3Division of Neurocritical Care, Department of Neurosurgery and Neurology, Seoul National University Bundang Hospital, Seongnam, Korea

Abstract

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is known as a maternally inherited mitochondrial disease with a m.3243A>G mutation in the MT-TL1 gene. Here, we report a case of targeted temperature management in a MELAS patient who had a cardiac arrest and severe lactic acidosis after recurrent seizures.

Keyword

MELAS syndrome; Acidosis; lactic; Targeted temperature management
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