Ann Dermatol.  2021 Aug;33(4):377-381. 10.5021/ad.2021.33.4.377.

Case of Rapidly Progressing Angiosarcoma after Total Hip Arthroplasty

  • 1Departments of Dermatology, School of Medicine, Keimyung University, Daegu, Korea
  • 2Departments of Orthopedic Surgery, School of Medicine, Keimyung University, Daegu, Korea


The occurrence of malignant tumor in proximity to an arthroplasty prosthesis has been a matter of debate since it was first reported in 1978. Upon considering the number of orthopedic implants used, the occurrence of malignancy is rare. Especially in case of angiosarcoma, only a few cases have been reported worldwide. In this case, we report an extremely rare case of angiosarcoma arising at the site of a revision total hip arthroplasty. A 69-year-old female had received total hip replacement on her left hip due to osteoarthritis 8 months ago. Four months later, she complained pain on her operated area, X-ray showed loosening of implanted cup on her left hip. Thereafter, erythematous and purpuric papules and nodules were developed and spread around on her left hip. Through the skin biopsy she was diagnosed with angiosarcoma, and then she died of a sharp deterioration. Herein, we report a rare case of angiosarcoma occurred after total hip replacement with a review of the literature.


Angiosarcoma; Arthroplasty; replacement; hip; Orthopedic procedures; Sarcoma
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