Korean J Adult Nurs.  2021 Jun;33(3):203-211. 10.7475/kjan.2021.33.3.203.

Factors related to Medication Adherence in Patients with Heart Failure

• So N
• Kim H

• KMID: 2517236
• DOI: http://doi.org/10.7475/kjan.2021.33.3.203

Abstract

Purpose
The purpose of this study was to determine the levels of medication adherence in patients with heart failure and explore the factors related to it.
Methods
Cross-sectional and descriptive surveys were conducted in 107 patients with heart failure who visited C Hospital in D City. Data were collected from patients using self-report questionnaires between May 2015 and November 2016, and their medical records were identified. Data were analyzed using independent t-test, one-way ANOVA, and correlation and hierarchical multiple regression analyses using SPSS.
Results
The mean score of medication adherence was 10.23±2.70. Patients with long-term adverse effects showed worse medication adherence than those without long-term adverse effects (t=2.55, p=.012). Medication adherence positively correlated with depression (r=.34, p=.001) and barriers (r=.48, p=.001) but negatively correlated with attitude (r=-.39, p=.001). The hierarchical multiple regression analysis showed that the model with two independent variables of long-term adverse effects (β=-.23, p=.008) and barriers (β=.37, p<.001) explained the 29.6% in medication adherence (F=11.93, p<.001).
Conclusion
To improve medication adherence, a nursing strategy to reduce long-term adverse effects and barriers accompanied by continuous monitoring is required.

Keyword

Medication adherence; Side effect; Depression; Attitude; Barriers