Biomol Ther.
2021 Jul;29(4):365-372. 10.4062/biomolther.2020.204.
Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management
- Affiliations
-
- 1Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar-608002, Tamilnadu, India
- 2Department of Pharmacology and Toxicology, Metabolic Diseases Research Laboratory, School of Dentistry, Kyung Hee University, Seoul 02447, Republic of Korea
- KMID: 2517154
- DOI: http://doi.org/10.4062/biomolther.2020.204
Abstract
- Type 2 diabetes mellitus (T2DM) leads to many health problems like diabetic nephropathy (DN). One of the key factors for chronic kidney disease and end-stage renal disease (ESRD) is T2DM. Extensive work is being done to delineate the pathogenesis of DN and to extend possible remedies. This review is intended to understand the nature of DN risk factors, progression, effects of glycemic levels, and stages of DN. We also explored the novel diagnostic and therapeutic approaches for DN such as gene therapy and stem cell treatments.
