J Lipid Atheroscler.
2021 May;10(2):129-129. 10.12997/jla.2021.10.2.123.
Bacterial Postbiotics as Promising Tools to Mitigate Cardiometabolic Diseases
- Affiliations
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- 1Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
- 2Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada
- 3Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada
- 4Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- 5Quebec Heart and Lung Research Institute, Laval University, Quebec, Canada
- KMID: 2516877
- DOI: http://doi.org/10.12997/jla.2021.10.2.123
Abstract
- Gut microbes dictate critical features of host immunometabolism. Certain bacterial components and metabolites (termed postbiotics) mitigate cardiometabolic diseases whereas others potentiate pathological processes. In this review, we discuss key aspects related to the usefulness of bacterial-related molecules strategically positioned as promising treatment strategies for cardiometabolic diseases.
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