Anxiety Mood.  2021 Apr;17(1):1-11. 10.24986/anxmod.2021.17.1.001.

Application of Transcranial Direct Current Stimulation in Obsessive-Compulsive Disorder

  • 1Air Force Education and Training Command Base Hospital, Jinju, Korea
  • 2Graduate School, Yonsei University College of Medicine, Seoul, Korea
  • 3Department of Psychiatry and Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea


Treating obsessive-compulsive disorder (OCD) is a difficult challenge since less than a half of the OCD patients show a significant treatment response to 1st line treatment. Therefore, various treatment tools in-cluding brain stimulation methods have been studied to solve the treatment-resistance of OCD. Transcranial direct current stimulation (tDCS) is one of the emerging treatment options for OCD. In this review, literatures on tDCS for OCD treatment were evaluated by assessing the treatment effects and safety issues. In most studies, tDCS caused a significant improvement in treatment-resistant OCD without serious adverse event, although its settings including electrode positions and polarity remain unestablished. Further studies are needed to develop protocols for applying tDCS in OCD and to strengthen the evidence of its efficacy.


Obsessive-compulsive disorder (OCD); Transcranial direct current stimulation (tDCS); Non-invasive brain stimulation.
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