Korean J Dent Mater.  2021 Mar;48(1):27-40. 10.14815/kjdm.2021.48.1.27.

Study on the characterization, biocompatibility and efficacy of sponge brush products for oral care

  • 1Department and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, Seoul, Republic of Korea
  • 2BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Republic of Korea
  • 3Department of Dental Hygiene, College of Medical Science, Konyang University, Daejeon, Republic of Korea


A sponge brush is an oral hygiene product that is used to clean buccal, gingival and palatal mucosa. The aim of this study was to observe the appearance, porosity, water sorption, cytotoxicity and efficacy of sponge brush products. Seven commercially available sponge brush products were used as test materials. To observe the appearance of sponge brush, the dimension and weight were examined. The porosity was measured using the micro CT. The water sorption rate was calculated by weight change before and after immersion of sponge brush in distilled water for 5 s. The sponge brush was extracted according to the KS P ISO 10993-12, and examined the extracted solution by visual inspection. Extracted solution was then evaluated with MTT assay. Protein removal efficacy of sponge brush product from the bovine serum albumin coated sheet was tested using bicinchoninic acid assay. The results of the length and diameter range of brush were 17~24 mm and 14~24 mm respectively. The length and thickness range of the handle was 14~16 cm and 3~5 mm respectively. There were significant differences in the sponge brush weight of all products (p<0.05), and porosity of the sponge was indicated to be more than 80% in all products. The water sorption rate ranged from 21 to 62% (p<0.05). As the results of extraction, there were neither foreign materials nor impurities in all of sponge brush products. The cell viability was indicated to be more than 70% except for two products. After applying all sponge brush products, the protein removal rate was more than 70%. The above results will provide useful information for future development of related oral care products.


Sponge brush; Porosity; Water sorption rate; Cytotoxicity; Protein removal effect
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