Korean J Otorhinolaryngol-Head Neck Surg.  2021 Mar;64(3):197-201. 10.3342/kjorl-hns.2020.00129.

A Case of a 50-Year Old Women with Cerebrospinal Fluid Rhinorrhea and Right Nasal Cavity Mass

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Dankook University College of Medicine, Cheonan, Korea


A 50-year-old woman visited the hospital with persistent watery rhinorrhea which she had for 2 months. Endoscopic examination revealed a mass in the right nasal cavity and rdiological findings revealed a bony defect on the lateral wall of the sphenoid sinus associated with the protrusion of the mass lesion. Endoscopic skull base reconstruction was performed via transpterygoid approach, including a watertight closure of the dural defect with both underlay and overlay repairs. Cerebrospinal fluid (CSF) leakage persisted after reconstruction. The right lateral lamella was identified as a secondary CSF leakage site. CSF leakage is common among patients with meningoencephalocele. However, a secondary CSF leakage accompanied with meningoencephalocele in other areas is uncommon. The present patient experienced CSF leakage from multiple sites—one associated with the original meningoencephalocele and another from a secondary defect at the skull base. This complication is rare in clinical practice. Here, we describe this rare case with a brief literature review.


Cerebrospinal fluid leakage; Fluorescein; Intrathecal injection; Encephalocele
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