Clin Exp Reprod Med.  2021 Mar;48(1):85-90. 10.5653/cerm.2020.03769.

Sperm retrieval by conventional testicular sperm extraction for assisted reproduction in patients with Zinner syndrome

• Cito G
• Gemma L
• Giachini C
• Micelli E
• Cocci A
• Fucci R
• Picone R
• Sforza S
• Nesi G
• Santi R
• Minervini A
• Masieri L
• Carini M
• Coccia ME
• Natali A

• KMID: 2513279
• DOI: http://doi.org/10.5653/cerm.2020.03769

Abstract

We present data from three Caucasian men with Zinner syndrome who attended our center for the treatment of primary couple’s infertility. Each patient was scheduled for conventional testicular sperm extraction (cTESE) and cryopreservation. Sperm analysis confirmed absolute azoospermia. Patient 1 had right and left testis volumes of 24 mL and 23 mL, respectively; left seminal vesicle (SV) agenesis, severe right SV hypotrophy with right renal agenesis. Follicle-stimulating hormone (FSH) was 3.2 IU/L. Patient 2 exhibited right and left testis volumes of 18 mL and 16 mL, respectively; a left SV cyst of 32 × 28 mm, ipsilateral kidney absence, and right SV agenesis. FSH was 2.8 IU/L. Patient 3 showed a testicular volume of 10 mL bilaterally, a 65 × 46 mm left SV cyst, right SV enlargement, and left kidney agenesis. FSH was 32.0 IU/L. Sperm retrieval was successful in all patients. Nevertheless, cTESE should be performed on the day of oocyte retrieval.

Keyword

Azoospermia; Infertility; Sperm retrieval; Testicular sperm extraction; Z Wolffian duct anomalies; Inner syndrome