J Korean Ophthalmol Soc.  2021 Feb;62(2):273-279. 10.3341/jkos.2021.62.2.273.

Evaluation of the Cone Contrast Sensitivity Test in Normal Eyes and those with Congenital Color Blindness

• Lee SH
• Chin HS
• Jung JW

• KMID: 2512949
• DOI: http://doi.org/10.3341/jkos.2021.62.2.273

Abstract

Purpose
We evaluated a new color vision test, thus the ColorDx Cone contrast test HD ([CCT-HD]; Konan Medical, Inc., Irvine, CA, USA) in normal and color vision-deficient (CVD) eyes of Koreans.
Methods
The CCT-HD was performed on 66 healthy Koreans (125 normal eyes) and 25 patients (50 eyes) with congenital CVD. The results from normal eyes were compared and analyzed in terms of binocular agreement, patient ages, and spherical equivalents. The CCT-HD results on CVD eyes were compared and analyzed.
Results
We found no significant difference in any of the long (L), medium (M), or short wavelength (S) cone cell sensitivity (L-CCT, M-CCT, S-CCT) scores for normal eyes; also, there was no significant effect of age and no significant correlation between the spherical equivalent and the CCT score. In normal eyes, all scores were >75 (normal ≥75). The average protan L-CCT score was significantly reduced (13.0 ± 13.2; p < 0.001) as was the average deutan M-CCT score (31.7 ± 16.6; p < 0.001). The CCT-HD L-CCT and M-CCT exhibited 100% sensitivity and specificity in terms of diagnosing protans and deutans respectively.
Conclusions
CCT-HD allows classification and quantitative evaluation of protans and deutans, and is thus useful when examining color vision status.

Keyword

Color vision test, Cone contrast sensitivity test, Congenital color vision deficiency