J Korean Ophthalmol Soc.  2021 Feb;62(2):222-229. 10.3341/jkos.2021.62.2.222.

Clinical Effects of Non-damaging Retinal Laser Therapy in Chronic Central Serous Chorioretinopathy

• Kim YW
• Lee KW
• Ahn JH
• Nam DH
• Lee DY

• KMID: 2512942
• DOI: http://doi.org/10.3341/jkos.2021.62.2.222

Abstract

Purpose
This study analyzed the effects of non-damaging retinal laser therapy (NRT) in patients with chronic central serous chorioretinopathy.
Methods
A retrospective study was conducted on patients with chronic central serous chorioretinopathy who were undergoing follow-up with NRT from November 2016 to February 2018. NRT was performed in patients who underwent intravitreal anti-vascular endothelial growth factor (anti-VEGF) injection at least two times with no improvement in visual acuity and a reduced amount of subretinal fluid. Before and after treatment, logMAR best-corrected visual acuity (BCVA) evaluation and subretinal fluid (SRF) according to thickness measurements of the macula determined from optical coherence tomography imagery were performed over a period of at least 6 months.
Results
Eighteen eyes of 18 patients (11 male and 7 female) with chronic central serous retinopathy were treated with NRT. The mean age of patients was 54.6 ± 13.19 years old and the mean duration of follow-up was 9.75 ± 3.20 months. The central macular thickness decreased from 375 to 246 nm (p < 0.001) and BCVA improved from 0.48 to 0.40 (p = 0.028). SRF completely resolved in 55.56% of the patients after NRT.
Conclusions
In patients with chronic central serous chorioretinopathy, which did not improve even after intravitreal anti-VEGF injection, NRT is a relatively safe and effective treatment.

Keyword

Central serous chorioretinopathy, Laser therapy