Ann Lab Med.  2021 Jul;41(4):355-356. 10.3343/alm.2021.41.4.355.

Hepcidin-25 as a Novel Kidney Biomarker for Cardiac Surgery-Associated Acute Kidney Injury

• Cho SY
• Hur M

• KMID: 2512713
• DOI: http://doi.org/10.3343/alm.2021.41.4.355

Keyword

Kidney biomarker; Cardiac surgery; Acute kidney injury

Reference

1. Wang Y, Bellomo R. 2017; Cardiac surgery-associated acute kidney injury: risk factors, pathophysiology and treatment. Nat Rev Nephrol. 13:697–711. DOI: 10.1038/nrneph.2017.119. PMID: 28869251.

2. Albert C, Haase M, Albert A, Kropf S, Bellomo R, Westphal S, et al. 2020; Urinary Biomarkers may complement the Cleveland score for prediction of adverse kidney events after cardiac surgery: a pilot study. Ann Lab Med. 40:131–41. DOI: 10.3343/alm.2020.40.2.131. PMID: 31650729. PMCID: PMC6822001.

3. Yuan SM. 2019; Acute kidney injury after cardiac surgery: risk Factors and novel biomarkers. Braz J Cardiovasc Surg. 34:352–60. DOI: 10.21470/1678-9741-2018-0212. PMID: 31310475. PMCID: PMC6629228.

4. Albert C, Haase M, Albert A, Ernst M, Kropf S, Bellomo R, et al. 2021; Predictive value of plasma NGAL:hepcidin-25 for major adverse kidney events after cardiac surgery with cardiopulmonary bypass: a pilot study. Ann Lab Med. 41:357–65. DOI: 10.3343/alm.2021.41.4.357. PMID: 33536353.

5. Haase-Fielitz A, Mertens PR, Plass M, Kuppe H, Hetzer R, Westerman M, et al. 2011; Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury: an observational cohort study. Crit Care. 15:R186. DOI: 10.1186/cc10339. PMID: 21816077. PMCID: PMC3387629.

6. Choi N, Whitlock R, Klassen J, Zappitelli M, Arora RC, Rigatto C, Ho J, et al. 2019; Early intraoperative iron-binding proteins are associated with acute kidney injury after cardiac surgery. J Thorac Cardiovasc Surg. 157:287–97. e2. DOI: 10.1016/j.jtcvs.2018.06.091. PMID: 30195593.