J Korean Soc Matern Child Health.  2021 Jan;25(1):42-47. 10.21896/jksmch.2021.25.1.42.

Comparison of Pregnancy Prognosis for Gestational Diabetes Diagnosed by the 1-Step and 2-Step Methods

• Park S
• Lee JH
• Kim BR
• Park MH
• Kim YJ

• KMID: 2512483
• DOI: http://doi.org/10.21896/jksmch.2021.25.1.42

Abstract

Purpose
To compare pregnancy complications between the 2 groups of patients with gestational diabetes mellitus (GDM): those diagnosed by the 1-step method and those diagnosed by the 2-step method.
Methods
In this retrospective cohort study, the data from outpatient and hospitalization medical records of 201 patients diagnosed with GDM between 2013 and 2017 were reviewed. We compared the pregnancy complications of these patients based on whether they were diagnosed by the 1-step or 2-step method. SPSS ver. 20.0 was used to analyze the data from the 2 groups. The odds ratio and 95% confidence interval of the pregnancy outcomes were estimated using binary logistic regression analysis.
Results
On comparing pregnancy-related complications between the groups, there was no significant difference in the incidence of preeclampsia or delivery by cesarean section (p>0.99 and p=0.50, respectively). In the 1-step and 2-step groups, the prevalence of premature birth was significantly high at 19.7 % and 40.3% (p=0.01), respectively. There were no significant differences between the 2 groups in terms of macrosomia, large for gestational age (LGA), small for gestational age (SGA), low APGAR score, and neonatal hypoglycemia (p>0.99, p>0.26, p>0.62, p>0.57, and p>0.45, respectively).
Conclusion
On comparing the 2 groups, we found that the 1-step and 2-step GDM groups had similar risks of pregnancy complications, namely preeclampsia, delivery by cesarean section, macrosomia, LGA, SGA, low APGAR scores, and neonatal hypoglycemia.

Keyword

Gestational diabetes, Gestational diabetes screening test, One-step method, Two-step method

Figure

• 

  Figure 1. Study scheme and number of participants in each group. GCT, glucose challenge test; OGTT, oral glucose tolerance test; DM, diabetes mellitus; IADPSG, International Association of Diabetes and Pregnancy Study Group; FPG, fasting plasma glucose; CC, Carpenter-Coustan.

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