J Korean Ophthalmol Soc.  2020 Dec;61(12):1548-1552. 10.3341/jkos.2020.61.12.1548.

Pseudopapilledema Combined with Idiopathic Papilledema in a Child Receiving Growth Hormone Treatment

• Lee HC
• Park CK

• KMID: 2511300
• DOI: http://doi.org/10.3341/jkos.2020.61.12.1548

Abstract

Purpose
We report a case of pseudopapilledema combined with idiopathic papilledema in a pediatric patient receiving growth hormone treatment.
Case summary
An 11-year-old girl without any underlying disease presented with bilateral transient visual obscurations, a dark-adaptation disorder, and helplessness that developed while she had been on growth hormone therapy for 3 months at a local clinic. Reduced visual acuity (from 20/20 to 20/25) was observed on physical examination and bilateral optic disc edema on fundus examination, growth hormone was immediately discontinued. Four weeks later, fundus examination revealed papilledema of both eyes with mild red-green dyschromatopsia. Recombinant growth hormone-associated idiopathic papilledema combined with pseudopapilledema was suspected. Although growth hormone, had been discontinued, we scheduled further observation of the papilledema.
Conclusions
Papilledema was observed on fundus examination during growth hormone treatment and four weeks after discontinuation thereof. The symptoms improved, but mild papilledema combined with pseudopapilledema remained.

Keyword

Growth hormone; Papilledema