J Biomed Transl Res.  2020 Dec;21(4):200-206. 10.12729/jbtr.2020.21.4.200.

Massive human Q fever outbreak from a goat farm in Korea

• Byeon HS
• Han MN
• Han ST
• Chae MH
• Kang SS
• Jang RH
• Kim CS
• Jeong HW
• Jeon BY
• Ahn B

• KMID: 2510286
• DOI: http://doi.org/10.12729/jbtr.2020.21.4.200

Abstract

We report a massive outbreak of human Q fever cases, which occurred at totally 11 humans. The occurrence was related to a goat farm where Coxiella burnetii infection was diagnosed from goat tissues and environmental specimens. From January of 2018, continuous abortions from 6 goats occurred. Laboratory tests from 77 goat specimens for C. burnetii showed that 54 (70.1%) and 63 (81.8%) goats were positive by polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA), respectively. The infection was also confirmed from the farmer, his wife and 9 persons from all 16 veterinary officials who had visited the farm for protective measures and preparing goat specimens for laboratory tests. The farm was found to be extensively contaminated with C. burnetii from the examination to the environmental specimens and epidemiological inspections, which might be the main source of C. burnetii infection to humans. The extensive contamination to the farm was derived from the uncareful handling of postpartum animal tissues or discharges by the farm owner. This report will contribute to the establishment of educational system on the biosecurity to novice farmers.

Keyword

Coxiella burnetii; goat farm; goat Q fever; human Q fever; poor biosecurity