Allergy Asthma Respir Dis.  2020 Oct;8(4):227-230. 10.4168/aard.2020.8.4.227.

Bee pollen-induced anaphylaxis: Report of a patient with oral allergy syndrome

  • 1Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea


Bee pollen is a mixture of pollen, nectar collected by honeybees, and digestive enzymes secreted from honeybees, which is consumed as a dietary supplement. We experienced a case of anaphylaxis after ingestion of bee pollen in a patient with seasonal allergic rhinitis and oral allergy syndrome caused by watermelons, Korean melons, peaches, and plums. The skin prick test was positive for bee pollen, dandelion, ragweed, and mugwort, and specific IgE to honeybee venom was negative. According to the literature, bee pollen causing systemic allergic reactions mainly consists of the plant family Compositae, including dandelion, ragweed, and mugwort. Thus, ingestion of bee pollen should be closely monitored in patients with allergic rhinitis worsening in autumn, especially those with oral allergy syndrome for foods that cross-react with weed pollen.


Anaphylaxis; Pollen; Bee; Oral allergy syndrome; Allergic rhinitis
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