Nucl Med Mol Imaging.  2020 Feb;54(1):63-64. 10.1007/s13139-019-00628-4.

Clinical Applications of ⁶⁸Ga-PSMA PET/CT on Residual Disease Assessment of Juvenile Nasopharyngeal Angiofibroma (JNA)

• Sakthivel P
• Thakar A
• Prashanth A
• Angamuthu M
• Sharma SC
• Kumar R

• KMID: 2507682
• DOI: http://doi.org/10.1007/s13139-019-00628-4

Abstract

We present a case of a 16-year-old boy who underwent ⁶⁸Ga-PSMA PET/CT for residual disease assessment of juvenile nasal angiofibroma. Positive uptake was noted in residual tumor on PET/CT imaging. However, there was no abnormal uptake in surrounding scar tissues as compared with contrast-enhanced magnetic resonance imaging. These findings were confirmed by biopsy from the scar tissue on posterior ethmoids. ⁶⁸Ga-PSMA PET/CT may be a potentially valuable tool especially in distinguishing recurrences from surgical site reparative tissue and in planning and delivering stereotactic radiotherapy.

Keyword

Angiofibroma; PSMA PET-CT; Juvenile nasopharyngeal angiofibroma; MRI