J Korean Soc Radiol.  2020 Sep;81(5):1234-1238. 10.3348/jksr.2019.0068.

Calcium Pyrophosphate Dihydrate Crystal Deposition Disease Involving the Ligamentum Flavum of the Cervical Spine with Intense Enhancement on MRI: A Case Report

Affiliations
  • 1Department of Radiology, Hanyang University Seoul Hospital, Seoul, Korea
  • 2Department of Pathology, National Police Hospital, Seoul, Korea

Abstract

Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is characterized by chondrocalcinosis, which mainly affects the knees, wrists, pelvis, and rarely, the spine. According to previous reports, CPPD crystal deposits display heterogeneous enhancement on MRI. When combined with inflammation of the surrounding soft tissue, strong enhancement by CPPD crystal deposition may appear similar to imaging features of other conditions such as infectious spondylitis. In these conditions, CT plays an important role in differential diagnosis. Here, we present a case of CPPD crystal deposition disease in the ligamentum flavum of the cervical spine that showed intense enhancement on MRI.

Keyword

Calcium Pyrophosphate; Chondrocalcinosis; Ligamentum Flavum; Magnetic Resonance Imaging
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