1. Laine L. 2016; Clinical practice. Upper gastrointestinal bleeding due to a peptic ulcer. N Engl J Med. 374:2367–2376. DOI:
10.1056/NEJMcp1514257. PMID:
27305194.
2. Laine L, Yang H, Chang SC, Datto C. 2012; Trends for incidence of hospitalization and death due to GI complications in the United States from 2001 to 2009. Am J Gastroenterol. 107:1190–1195. quiz 1196. DOI:
10.1038/ajg.2012.168. PMID:
22688850.
Article
4. Tielleman T, Bujanda D, Cryer B. 2015; Epidemiology and risk factors for upper gastrointestinal bleeding. Gastrointest Endosc Clin N Am. 25:415–428. DOI:
10.1016/j.giec.2015.02.010. PMID:
26142028.
Article
5. Gralnek IM, Dumonceau JM, Kuipers EJ, et al. 2015; Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy. 47:a1–a46. DOI:
10.1055/s-0034-1393172. PMID:
26417980.
Article
7. Lee JH, Choi KD, Jung HY, et al. 2018; Seroprevalence of Helicobacter pylori in Korea: a multicenter, nationwide study conducted in 2015 and 2016. Helicobacter. 23:e12463. DOI:
10.1111/hel.12463. PMID:
29345022. PMCID:
PMC5900911.
10. Wang CY, Qin J, Wang J, Sun CY, Cao T, Zhu DD. 2013; Rockall score in predicting outcomes of elderly patients with acute upper gastrointestinal bleeding. World J Gastroenterol. 19:3466–3472. DOI:
10.3748/wjg.v19.i22.3466. PMID:
23801840. PMCID:
PMC3683686.
Article
11. Cieniawski D, Kuźniar E, Winiarski M, Matłok M, Kostarczyk W, Pedziwiatr M. 2013; Prognostic value of the Rockall score in patients with acute nonvariceal bleeding from the upper gastrointestinal tract. Przegl Lek. 70:1–5. PMID:
23789296.
12. Blatchford O, Davidson LA, Murray WR, Blatchford M, Pell J. 1997; Acute upper gastrointestinal haemorrhage in west of Scotland: case ascertainment study. BMJ. 315:510–514. DOI:
10.1136/bmj.315.7107.510. PMID:
9329304. PMCID:
PMC2127364.
Article
13. Stanley AJ, Ashley D, Dalton HR, et al. 2009; Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation. Lancet. 373:42–47. DOI:
10.1016/S0140-6736(08)61769-9. PMID:
19091393.
Article
14. Saltzman JR, Tabak YP, Hyett BH, Sun X, Travis AC, Johannes RS. 2011; A simple risk score accurately predicts in-hospital mortality, length of stay, and cost in acute upper GI bleeding. Gastrointest Endosc. 74:1215–1224. DOI:
10.1016/j.gie.2011.06.024. PMID:
21907980.
Article
15. Green FW Jr, Kaplan MM, Curtis LE, Levine PH. 1978; Effect of acid and pepsin on blood coagulation and platelet aggregation. A possible contributor prolonged gastroduodenal mucosal hemorrhage. Gastroenterology. 74:38–43. DOI:
10.1016/0016-5085(78)90352-9. PMID:
21830.
16. Lau JY, Leung WK, Wu JC, et al. 2007; Omeprazole before endoscopy in patients with gastrointestinal bleeding. N Engl J Med. 356:1631–1640. DOI:
10.1056/NEJMoa065703. PMID:
17442905.
Article
17. Sreedharan A, Martin J, Leontiadis GI, et al. 2010; Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding. Cochrane Database Syst Rev. (7):CD005415. DOI:
10.1002/14651858.CD005415.pub3. PMID:
20614440. PMCID:
PMC6769021.
Article
18. Bardou M, Toubouti Y, Benhaberou-Brun D, Rahme E, Barkun AN. 2005; Meta-analysis: proton-pump inhibition in high-risk patients with acute peptic ulcer bleeding. Aliment Pharmacol Ther. 21:677–686. DOI:
10.1111/j.1365-2036.2005.02391.x. PMID:
15771753.
Article
19. Laine L, McQuaid KR. 2009; Endoscopic therapy for bleeding ulcers: an evidence-based approach based on meta-analyses of randomized controlled trials. Clin Gastroenterol Hepatol. 7:33–47. DOI:
10.1016/j.cgh.2008.08.016. PMID:
18986845.
Article
20. Jensen DM, Pace SC, Soffer E, Comer GM. 315 Study Group. 2006; Continuous infusion of pantoprazole versus ranitidine for prevention of ulcer rebleeding: a U.S. multicenter randomized, double-blind study. Am J Gastroenterol. 101:1991–1999. DOI:
10.1111/j.1572-0241.2006.00773.x. PMID:
16968504.
Article
21. Karstensen JG, Ebigbo A, Aabakken L, et al. 2018; Nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) cascade guideline. Endosc Int Open. 6:E1256–E1263. DOI:
10.1055/a-0677-2084. PMID:
30302383. PMCID:
PMC6175685.
Article
23. Sachar H, Vaidya K, Laine L. 2014; Intermittent vs continuous proton pump inhibitor therapy for high-risk bleeding ulcers: a systematic review and meta-analysis. JAMA Intern Med. 174:1755–1762. DOI:
10.1001/jamainternmed.2014.4056. PMID:
25201154. PMCID:
PMC4415726.
24. Wysocki JD, Srivastav S, Winstead NS. 2012; A nationwide analysis of risk factors for mortality and time to endoscopy in upper gastrointestinal haemorrhage. Aliment Pharmacol Ther. 36:30–36. DOI:
10.1111/j.1365-2036.2012.05129.x. PMID:
22577955.
Article
25. Laursen SB, Leontiadis GI, Stanley AJ, Møller MH, Hansen JM, Schaffalitzky de Muckadell OB. 2017; Relationship between timing of endoscopy and mortality in patients with peptic ulcer bleeding: a nationwide cohort study. Gastrointest Endosc. 85:936–944.e3. DOI:
10.1016/j.gie.2016.08.049. PMID:
27623102.
27. Cho SH, Lee YS, Kim YJ, et al. 2018; Outcomes and role of urgent endoscopy in high-risk patients with acute nonvariceal gastrointestinal bleeding. Clin Gastroenterol Hepatol. 16:370–377. DOI:
10.1016/j.cgh.2017.06.029. PMID:
28634135.
Article
28. Restellini S, Kherad O, Jairath V, Martel M, Barkun AN. 2013; Red blood cell transfusion is associated with increased rebleeding in patients with nonvariceal upper gastrointestinal bleeding. Aliment Pharmacol Ther. 37:316–322. DOI:
10.1111/apt.12170. PMID:
23205554.
Article
29. Fabricius R, Svenningsen P, Hillingsø J, Svendsen LB, Sillesen M. 2016; Effect of transfusion strategy in acute non-variceal upper gastrointestinal bleeding: a nationwide study of 5861 hospital admissions in Denmark. World J Surg. 40:1129–1136. DOI:
10.1007/s00268-015-3370-4. PMID:
26675926.
Article
30. Subramaniam K, Spilsbury K, Ayonrinde OT, et al. 2016; Red blood cell transfusion is associated with further bleeding and fresh-frozen plasma with mortality in nonvariceal upper gastrointestinal bleeding. Transfusion. 56:816–826. DOI:
10.1111/trf.13446. PMID:
26718025.
Article
31. Hajiagha Mohammadi AA, Reza Azizi M. 2019; Prognostic factors in patients with active non-variceal upper gastrointestinal bleeding. Arab J Gastroenterol. 20:23–27. DOI:
10.1016/j.ajg.2019.01.001. PMID:
30770260.
Article
34. Blair SD, Janvrin SB, McCollum CN, Greenhalgh RM. 1986; Effect of early blood transfusion on gastrointestinal haemorrhage. Br J Surg. 73:783–785. DOI:
10.1002/bjs.1800731007. PMID:
3533203.
Article
35. Hearnshaw SA, Logan RF, Palmer KR, Card TR, Travis SP, Murphy MF. 2010; Outcomes following early red blood cell transfusion in acute upper gastrointestinal bleeding. Aliment Pharmacol Ther. 32:215–224. DOI:
10.1111/j.1365-2036.2010.04348.x. PMID:
20456308.
Article
36. Villanueva C, Colomo A, Bosch A, et al. 2013; Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med. 368:11–21. DOI:
10.1056/NEJMoa1211801. PMID:
23281973.
Article
37. Jairath V, Kahan BC, Gray A, et al. 2015; Restrictive versus liberal blood transfusion for acute upper gastrointestinal bleeding (TRIGGER): a pragmatic, open-label, cluster randomised feasibility trial. Lancet. 386:137–144. DOI:
10.1016/S0140-6736(14)61999-1. PMID:
25956718.
39. Lau JY, Sung JJ, Chan AC, et al. 1997; Stigmata of hemorrhage in bleeding peptic ulcers: an interobserver agreement study among international experts. Gastrointest Endosc. 46:33–36. DOI:
10.1016/S0016-5107(97)70206-2. PMID:
9260702.
Article
40. Bleau BL, Gostout CJ, Sherman KE, et al. 2002; Recurrent bleeding from peptic ulcer associated with adherent clot: a randomized study comparing endoscopic treatment with medical therapy. Gastrointest Endosc. 56:1–6. DOI:
10.1067/mge.2002.125365. PMID:
12085028.
Article
42. Harris JM, DiPalma JA. 1993; Clinical significance of Mallory-Weiss tears. Am J Gastroenterol. 88:2056–2058. PMID:
8249973.
43. Ljubičić N, Budimir I, Pavić T, et al. 2014; Mortality in high-risk patients with bleeding Mallory-Weiss syndrome is similar to that of peptic ulcer bleeding. Results of a prospective database study. Scand J Gastroenterol. 49:458–464. DOI:
10.3109/00365521.2013.846404. PMID:
24495010.
Article
44. Chung IK, Kim EJ, Hwang KY, et al. 2002; Evaluation of endoscopic hemostasis in upper gastrointestinal bleeding related to Mallory-Weiss syndrome. Endoscopy. 34:474–479. DOI:
10.1055/s-2002-32000. PMID:
12048631.
Article
45. Bharucha AE, Gostout CJ, Balm RK. 1997; Clinical and endoscopic risk factors in the Mallory-Weiss syndrome. Am J Gastroenterol. 92:805–808. PMID:
9149189.
46. Kortas DY, Haas LS, Simpson WG, Nickl NJ 3rd, Gates LK Jr. 2001; Mallory-Weiss tear: predisposing factors and predictors of a complicated course. Am J Gastroenterol. 96:2863–2865. DOI:
10.1111/j.1572-0241.2001.04239.x. PMID:
11693318.
Article
47. Kim JW, Kim HS, Byun JW, et al. 2005; Predictive factors of recurrent bleeding in Mallory-Weiss syndrome. Korean J Gastroenterol. 46:447–454. PMID:
16371719.
48. Park CH, Min SW, Sohn YH, et al. 2004; A prospective, randomized trial of endoscopic band ligation vs.epinephrine injection for actively bleeding Mallory-Weiss syndrome. Gastrointest Endosc. 60:22–27. DOI:
10.1016/S0016-5107(04)01284-2. PMID:
15229420.
49. Huang SP, Wang HP, Lee YC, et al. 2002; Endoscopic hemoclip placement and epinephrine injection for Mallory-Weiss syndrome with active bleeding. Gastrointest Endosc. 55:842–846. DOI:
10.1067/mge.2002.124560. PMID:
12024138.
Article
50. Lee S, Ahn JY, Jung HY, et al. 2016; Effective endoscopic treatment of Mallory-Weiss syndrome using Glasgow-Blatchford score and Forrest classification. J Dig Dis. 17:676–684. DOI:
10.1111/1751-2980.12409. PMID:
27624697.
Article
51. Lecleire S, Antonietti M, Iwanicki-Caron I, et al. 2009; Endoscopic band ligation could decrease recurrent bleeding in Mallory-Weiss syndrome as compared to haemostasis by hemoclips plus epinephrine. Aliment Pharmacol Ther. 30:399–405. DOI:
10.1111/j.1365-2036.2009.04051.x. PMID:
19485979.
Article
52. Shimoda R, Iwakiri R, Sakata H, et al. 2009; Endoscopic hemostasis with metallic hemoclips for iatrogenic Mallory-Weiss tear caused by endoscopic examination. Dig Endosc. 21:20–23. DOI:
10.1111/j.1443-1661.2008.00825.x. PMID:
19691796.
Article
53. Saltzman JR, Strate LL, Di Sena V, et al. 2005; Prospective trial of endoscopic clips versus combination therapy in upper GI bleed-ing (PROTECCT--UGI bleeding). Am J Gastroenterol. 100:1503–1508. DOI:
10.1111/j.1572-0241.2005.41561.x. PMID:
15984972.
Article
54. Barakat M, Hamed A, Shady A, Homsi M, Eskaros S. 2018; Endoscopic band ligation versus endoscopic hemoclip placement for Dieulafoy's lesion: a meta-analysis. Eur J Gastroenterol Hepatol. 30:995–996. DOI:
10.1097/MEG.0000000000001179. PMID:
30048368.
Article
55. Senger JL, Kanthan R. 2012; The evolution of Dieulafoy's lesion since 1897: then and now-a journey through the lens of a pediatric lesion with literature review. Gastroenterol Res Pract. 2012:432517. DOI:
10.1155/2012/432517. PMID:
22474434. PMCID:
PMC3296298.
Article
57. Chung IK, Kim EJ, Lee MS, et al. 2000; Bleeding Dieulafoy's lesions and the choice of endoscopic method: comparing the hemostatic efficacy of mechanical and injection methods. Gastrointest Endosc. 52:721–724. DOI:
10.1067/mge.2000.108040. PMID:
11115902.
Article
58. Gisbert JP, Khorrami S, Carballo F, Calvet X, Gene E, Dominguez-Muñoz E. 2004; Meta-analysis: Helicobacter pylori eradication therapy vs. antisecretory non-eradication therapy for the prevention of recurrent bleeding from peptic ulcer. Aliment Pharmacol Ther. 19:617–629. DOI:
10.1111/j.1365-2036.2004.01898.x. PMID:
15023164.
59. Huang TC, Lee CL. 2014; Diagnosis, treatment, and outcome in patients with bleeding peptic ulcers and Helicobacter pylori infections. Biomed Res Int. 2014:658108. DOI:
10.1155/2014/658108. PMID:
25101293. PMCID:
PMC4101224.
63. Kim HK, Kim JS, Kim TH, et al. 2012; Effect of high-dose oral rabeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers. Gastroenterol Res Pract. 2012:317125. DOI:
10.1155/2012/317125. PMID:
23049546. PMCID:
PMC3463177.
Article
64. Sung JJ, Suen BY, Wu JC, et al. 2014; Effects of intravenous and oral esomeprazole in the prevention of recurrent bleeding from peptic ulcers after endoscopic therapy. Am J Gastroenterol. 109:1005–1010. DOI:
10.1038/ajg.2014.105. PMID:
24777150.
Article
65. El Ouali S, Barkun AN, Wyse J, et al. 2012; Is routine second-look en-doscopy effective after endoscopic hemostasis in acute peptic ulcer bleeding? A meta-analysis. Gastrointest Endosc. 76:283–292. DOI:
10.1016/j.gie.2012.04.441. PMID:
22695209.
66. Imperiale TF, Kong N. 2012; Second-look endoscopy for bleeding peptic ulcer disease: a decision-effectiveness and cost-effectiveness analysis. J Clin Gastroenterol. 46:e71–e75. DOI:
10.1097/MCG.0b013e3182410351. PMID:
22298087. PMCID:
PMC3343187.
67. Biondi-Zoccai GG, Lotrionte M, Agostoni P, et al. 2006; A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50,279 patients at risk for coronary artery disease. Eur Heart J. 27:2667–2674. DOI:
10.1093/eurheartj/ehl334. PMID:
17053008.
69. Derogar M, Sandblom G, Lundell L, et al. 2013; Discontinuation of low-dose aspirin therapy after peptic ulcer bleeding increases risk of death and acute cardiovascular events. Clin Gastroenterol Hepatol. 11:38–42. DOI:
10.1016/j.cgh.2012.08.034. PMID:
22975385.
Article
70. Eisenberg MJ, Richard PR, Libersan D, Filion KB. 2009; Safety of short-term discontinuation of antiplatelet therapy in patients with drugeluting stents. Circulation. 119:1634–1642. DOI:
10.1161/CIRCULATIONAHA.108.813667. PMID:
19289638.
Article
71. Hur S, Jae HJ, Lee H, Lee M, Kim HC, Chung JW. 2017; Superselective embolization for arterial upper gastrointestinal bleeding using N-butyl cyanoacrylate: a single-center experience in 152 patients. J Vasc Interv Radiol. 28:1673–1680. DOI:
10.1016/j.jvir.2017.07.027. PMID:
28935474.
72. Beggs AD, Dilworth MP, Powell SL, Atherton H, Griffiths EA. 2014; A systematic review of transarterial embolization versus emergency surgery in treatment of major nonvariceal upper gastrointestinal bleeding. Clin Exp Gastroenterol. 7:93–104. DOI:
10.2147/CEG.S56725. PMID:
24790465. PMCID:
PMC3998850.
Article
73. Loffroy R, Estivalet L, Cherblanc V, et al. 2012; Transcatheter embolization as the new reference standard for endoscopically unmanageable upper gastrointestinal bleeding. World J Gastrointest Surg. 4:223–227. DOI:
10.4240/wjgs.v4.i10.223. PMID:
23467300. PMCID:
PMC3587468.
Article
74. Wang YR, Richter JE, Dempsey DT. 2010; Trends and outcomes of hospitalizations for peptic ulcer disease in the United States, 1993 to 2006. Ann Surg. 251:51–58. DOI:
10.1097/SLA.0b013e3181b975b8. PMID:
20009753.
Article
75. Guglielmi A, Ruzzenente A, Sandri M, et al. 2002; Risk assessment and prediction of rebleeding in bleeding gastroduodenal ulcer. Endoscopy. 34:778–786. DOI:
10.1055/s-2002-34261. PMID:
12244498.
Article
76. Chung IK, Kim EJ, Lee MS, et al. 2001; Endoscopic factors predisposing to rebleeding following endoscopic hemostasis in bleeding peptic ulcers. Endoscopy. 33:969–975. DOI:
10.1055/s-2001-17951. PMID:
11668406.
Article