Korean J Vet Res.  2020 Jun;60(2):97-100. 10.14405/kjvr.2020.60.2.97.

Splenic myxoid liposarcoma in a dog

Affiliations
  • 1Department of Veterinary Pathology and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea
  • 2POSTBIO, Inc., Guri 11906, Korea
  • 3Howon Animal Medical Center, Uijeongbu 11704, Korea
  • 4Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon 34140, Korea

Abstract

A 7-year-old Maltese was presented to a veterinary clinic for a history of anorexia, soft feces, and anemia. During abdominal sonography and computed tomography imaging, splenic mass was suspected. Laparotomy revealed the bloody ascites, and the enlarged spleen containing a large spherical mass. Microscopically, the splenic parenchyma was replaced by neoplastic cells with cytoplasmic vacuolation and abundant myxoid matrix. Cellular vacuolation and myxoid matrix were positive to Oil-Red-O and Alcian-blue stains. The neoplastic cells were positive to vimentin on immunohistochemistry. The case was diagnosed as myxoid liposarcoma. Based on a poor prognosis, the dog was euthanized three weeks after splenectomy.

Keyword

A 7-year-old Maltese was presented to a veterinary clinic for a history of anorexia, soft feces, and anemia. During abdominal sonography and computed tomography imaging, splenic mass was suspected. La; immunohistochemistry; liposarcoma; myxoid; spleen
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