Korean J Dermatol.  2020 Mar;58(3):191-195.

Two Cases of Orofacial Granulomatosis

• Kwon BR
• Choi MJ
• Byun JY
• Choi YW
• Choi HY

Abstract

Orofacial granulomatosis (OFG) is a rare chronic granulomatous disease of oral mucosa and maxillofacial region that clinically presents recurrent or persistent orofacial swelling. OFG may exist as an integration of the spectrum of various disorders, including Melkersson-Rosenthal syndrome, granulomatous cheilitis, Crohn’s disease, sarcoidosis, infectious diseases and delayed hypersensitivity reaction to food additives, dental materials. Precise etiology is not yet to be elucidated. Herein, we report two rare cases of orofacial granulomatosis who presented similar clinical manifestation of lip swelling but was diagnosed as a sarcoidosis and as a granulomatous cheilitis.

Keyword

Granulomatous cheilitis; Melkersson-Rosenthal syndrome; Orofacial granulomatosis, Sarcoidosis