Korean J Head Neck Oncol.
2020 May;36(1):39-44. 10.21593/kjhno/2020.36.1.39.
A Treatment of Basal cell Carcinoma on the Face of a Xeroderma Pigmentosum Patient: A Case Report
- Affiliations
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- 1Department of Plastic and Reconstructive Surgery, Konkuk University Medical Center, Seoul, Korea
- 2Department of Pathology, Konkuk University Medical Center, Seoul, Korea
- KMID: 2502689
- DOI: http://doi.org/10.21593/kjhno/2020.36.1.39
Abstract
- Xeroderma pigmentosum is a rare autosomal recessive disease, related to defects in DNA repair mechanism. It presents skin lesions on sun-exposed areas, leading to various skin cancer. Skin lesions can be treated with cryotherapy, skin resurfacing, 5-FU, Imiquimod, topical T4 endonuclease V, radiotherapy and genetic therapy, but invasive skin cancer should be treated by a surgery. We report a 12-year-old female xeroderma pigmentosum patient with recurrent basal cell carcinoma successfully treated by skin grafting. In that there is no cure for this disease, prevention and patient education is most important.
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