Ann Lab Med.  2020 Sep;40(5):414-416. 10.3343/alm.2020.40.5.414.

Bone Marrow Gouty Tophi With Plasma Cell Myeloma

Affiliations
  • 1Departments of Laboratory Medicin, Soonchunhyang University Seoul Hospital, Seoul, Korea
  • 2Departments of Pathology, Soonchunhyang University Seoul Hospital, Seoul, Korea


Figure

  • Fig. 1 Bone marrow (BM) aspirate smear and biopsy findings. (A) Plasma cells on the BM aspirate smear (Wright-Giemsa stain, ×400). (B, C) Fine, needle-shaped, radially oriented crystals surrounded by foreign-body type giant cells on the BM section (hematoxylin and eosin stain, ×100 and ×200). (D) Shiny, strong negatively birefringent crystals against a dark background observed by birefringence microscopy, consistent with uric acid crystals (hematoxylin and eosin stain, ×200).


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