Ann Dermatol.  2020 Jun;32(3):223-229. 10.5021/ad.2020.32.3.223.

Eccrine Porocarcinoma: A Multicenter Retrospective Study with Review of the Literatures Reported in Korea

Affiliations
  • 1Department of Dermatology, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea
  • 2Departments of Dermatology, College of Medicine, Korea University, Seoul, Korea
  • 3Departments of Plastic Surgery, College of Medicine, Korea University, Seoul, Korea
  • 4Departments of Pathology, College of Medicine, Korea University, Seoul, Korea

Abstract

Background
Eccrine porocarcinoma (EPC) is a rare malignant cutaneous adnexal tumor. Other than several scattered case reports, no comprehensive review on EPC has been conducted in Korea.
Objective
To clinicopathologically review all EPC cases from our institutions as well as those reported in Korea.
Methods
Medical records and histopathological slides of EPC cases in the skin biopsy registries of our institutions were retrospectively reviewed. Additionally, EPC cases reported in Korea before June 2019 were retrieved by searching the PubMed, KoMCI, KoreaMed, and KMbase databases.
Results
Nine EPC cases from our institutions were included in the study. In addition, 27 reports of 28 patients with EPC were reported in Korea. A total of 37 patients with EPC were identified, consisting of 19 males (male:female ratio, 1.06:1; mean age at diagnosis, 65.6 years). The most common site of primary tumor was the head and neck (29.7%). Wide excision was the most common (78.4%) treatment method. Initial metastasis work-up imaging studies were performed in 18 patients (48.6%), and metastasis was confirmed in eight patients (21.6%).
Conclusion
EPC is a rare cutaneous carcinoma in Korea. EPC usually affects elderly patients, with no sexual predilection. Due to possible metastasis, careful diagnosis and appropriate metastasis workups are warranted in EPC.

Keyword

Eccrine porocarcinoma; Malignant eccrine poroma; Porocarcinoma
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