Korean J Schizophr Res.  2020 Apr;23(1):1-7. 10.16946/kjsr.2020.23.1.1.

Factors Affecting the Duration of Untreated Psychosis in Community-Dwelling Patients with Schizophrenia Spectrum Disorder

Affiliations
  • 1Gwangju Mental Health and Welfare Commission, Gwangju, Korea
  • 2Department of Nursing, Graduate School, Chonnam National University, Gwangju, Korea
  • 3MindLink, Gwangju Bukgu Community Mental Health Center, Gwangju, Korea
  • 4Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea
  • 5GyeongGi-Do Mental Health and Welfare Center, Suwon, Korea

Abstract


Objectives
This study aimed to identify factors affecting the duration of untreated psychosis (DUP) in patients with schizophrenia spectrum disorder.
Methods
Six-hundred patients with schizophrenia spectrum disorder were recruited from mental health welfare centers in Gwangju Metropolitan City and Gyeonggi-do. Subjects were categorized into two groups according to median DUP. Demographic and clinical characteristics were compared between the two groups.
Results
The mean DUP was 80.8 weeks, and the median DUP was 15.9 weeks. Patients with Medicaid, higher age, and longer duration of the schizophrenia prodrome were more likely to have a longer DUP. The DUP was shorter in patients who were consulted by family/relatives prior to treatment. Patients visiting university hospitals were more likely to have a shorter DUP compared with those visiting psychiatric clinics or small-sized mental hospitals, i.e., with less than 100 beds. A multivariate regression analysis showed that the duration of the prodrome was a factor that significantly affected DUP.
Conclusion
The vulnerable group of patients with schizophrenia with a long DUP should be monitored closely. Moreover, it is necessary to develop a strategy to identify patients who have an insidious course of psychosis to reduce the DUP.

Keyword

Community; Duration of untreated psychosis (DUP); Early intervention; Psychosis; Schizophrenia
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