J Korean Ophthalmol Soc.  2020 Apr;61(4):376-384. 10.3341/jkos.2020.61.4.376.

Optic Nerve Head Parameters of Healthy Children as Measured by OpticalCoherence Tomography

• Lee JM
• Hwang YH

• KMID: 2500102
• DOI: http://doi.org/10.3341/jkos.2020.61.4.376

Abstract

Purpose
To investigate optic nerve head (ONH) parameters as measured using optical coherence tomography (OCT) in healthy children.
Methods
Peripapillary areas were scanned by spectral-domain OCT in healthy eyes of children aged 5–17 years. ONH parameters were automatically determined by OCT, including the rim area, disc area, cup-to-disc ratio, and cup volume. The effects of age and refractive error on ONH parameters were evaluated.
Results
A total of 352 eyes of 352 subjects (mean age: 9.7 ± 3.6 years) were enrolled. The mean rim area, disc area, cup-to-disc ratio, and cup volume was 1.51 ± 0.27 mm2, 2.07 ± 0.39 mm2, 0.47 ± 0.16, and 0.163 ± 0.148 mm3, respectively. The mean rim area, disc area, cup-to-disc ratio by age was 1.58 ± 0.29 mm2, 2.18 ± 0.35 mm2, and 0.48 ± 0.17 in 5- to 8-year-olds; 1.46 ± 0.24 mm2, 2.04 ± 0.43 mm2, and 0.49 ± 0.15 for 9- to 12-year-olds; and 1.46 ± 0.22 mm2, 1.94 ± 0.35 mm2, and 0.44 ± 0.18 for 13- to 17-year-old. Higher myopia and older age were associated with a smaller rim area (p < 0.05).
Conclusions
The mean rim area, disc area, and cup-to-disc ratio as measured using OCT in healthy children were 1.51 mm2, 2.07 mm2, and 0.47, respectively. ONH parameters were significantly affected by age and refractive error.

Keyword

Age; Children; Optical coherence tomography; Optic disc; Optic nerve head