Obstet Gynecol Sci.  2020 Mar;63(2):158-163. 10.5468/ogs.2020.63.2.158.

Prognostic value of lymph node ratio in surgically treated cases of vulvar cancer: a tertiary care centre experience

Affiliations
  • 1Department of Gynecological Oncology, Gujarat Cancer & Research Institute, Ahmedabad, India. drshilpamukesh@gmail.com

Abstract


OBJECTIVE
This study aimed to study the patterns of recurrence in surgically treated cases of vulvar cancer (VC) and determine the factors associated with recurrence, with a special emphasis on lymph node ratio (LNR).
METHODS
This retrospective study examined VC patients primarily treated with surgery at our institute from January 2005 to December 2015. Demographic data, clinical characteristics, surgicohistopathological data, adjuvant treatment, follow up, and recurrence site and treatment were studied.
RESULTS
Among the 111 cases treated, a recurrence rate of 18.9% was noted. Recurrence was most commonly local (61.9%). On univariate and multivariable analyses of clinicopathological parameters, an LNR >20 had the highest hazard ratio for recurrence.
CONCLUSION
LNR may provide useful prognostic information in VC patients with positive inguinal lymph node status.

Keyword

Vulvar cancer; Lymph node ratio; Recurrence; Radiotherapy

MeSH Terms

Follow-Up Studies
Humans
Lymph Nodes*
Radiotherapy
Recurrence
Retrospective Studies
Tertiary Healthcare*
Vulvar Neoplasms*
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