Ann Dermatol.  2020 Apr;32(2):151-154. 10.5021/ad.2020.32.2.151.

Two Cases of Aquagenic Wrinkling of the Palms in Korean Healthy Women: Easily Overlooked Disease

Affiliations
  • 1Department of Dermatology, Chosun University Medical School, Gwangju, Korea. inho-yoga@hanmail.net

Abstract

Aquagenic wrinkling of the palms (AWP) is a rare condition, which is characterized by appearance of whitish papules and plaques and an excessive wrinkling and swelling of the palmar skin after exposure to water. Herein, we report two cases of AWP. A 17-year-old woman presented prickling focal various sized whitish papules, plaques with wrinkles on both palms after water contact for 6 months ago. Histologic findings were consistent with AWP. A 26-year-old woman presented asymptomatic multiple various sized whitish papules, plaques with wrinkles on both palms after water contact for 1 year ago. Both patients underwent a cystic fibrosis transmembrane conduct receptor test but were negative and improved without any treatment.

Keyword

Aquagenic wrinkling of the palms; Cystic fibrosis

MeSH Terms

Adolescent
Adult
Cystic Fibrosis
Female
Humans
Skin
Water
Water
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