Korean J Radiol.  2020 Mar;21(3):325-331. 10.3348/kjr.2019.0508.

Magnetic Resonance Imaging Findings Differentiating Cutaneous Basal Cell Carcinoma from Squamous Cell Carcinoma in the Head and Neck Region

Affiliations
  • 1Department of Radiology, Gifu University School of Medicine, Gifu, Japan. hkato@gifu-u.ac.jp
  • 2Department of Tumor Pathology, Gifu University School of Medicine, Gifu, Japan.
  • 3Department of Pathology, Gifu University School of Medicine, Gifu, Japan.
  • 4Department of Dermatology, Gifu University School of Medicine, Gifu, Japan.

Abstract


OBJECTIVE
This study aimed to evaluate the efficacy of magnetic resonance (MR) imaging in differentiating between cutaneous basal cell carcinoma (cBCC) and cutaneous squamous cell carcinoma (cSCC) in the head and neck region.
MATERIALS AND METHODS
Among patients with cutaneous head and neck cancers, 14 with primary cBCCs and 15 with primary cSCCs with a histologic tumor height of ≥ 4 mm underwent MR examinations; the findings were then examined for correlations.
RESULTS
cBCCs (71%) occurred more frequently on the nose than cSCCs (13%) (p < 0.01). The maximum diameter (23.5 ± 7.2 mm vs. 12.7 ± 4.5 mm; p < 0.01) and diameter-to-height ratio (2.8 ± 0.9 vs. 1.7 ± 0.4; p < 0.01) were significantly greater in cSCCs than in cBCCs. Superficial ulcer formation (67% vs. 21%; p < 0.05), protrusion into the subcutaneous tissue (60% vs. 21%; p < 0.05), ill-demarcated deep tumor margins (60% vs. 7%; p < 0.01), and peritumoral fat stranding (93% vs. 7%; p < 0.01) were more frequently observed in cSCCs than in cBCCs. Intratumoral T2-hyperintense foci (57% vs. 13%; p < 0.05) were more frequently observed in cBCCs than in cSCCs.
CONCLUSION
cBCCs predominantly occurred on the nose with intratumoral T2-hyperintense foci, whereas cSCCs predominantly exhibited a flattened configuration, superficial ulcer formation, protrusion into the subcutaneous tissue, ill-demarcated deep tumor margin, and peritumoral fat stranding.

Keyword

Basal cell carcinoma; Squamous cell carcinoma; Skin cancer; Head and neck; MRI

MeSH Terms

Carcinoma, Basal Cell*
Carcinoma, Squamous Cell*
Epithelial Cells*
Head*
Humans
Magnetic Resonance Imaging*
Neck*
Nose
Skin Neoplasms
Subcutaneous Tissue
Ulcer
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