J Korean Burn Soc.
2019 Dec;22(2):45-48. 10.0000/jkbs.2019.22.2.45.
Feasibility of Cultured Allogenic Keratinocyte Treatment for Third Degree Burns
- Affiliations
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- 1Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea. jsn7190@catholic.ac.kr
- KMID: 2469248
- DOI: http://doi.org/10.0000/jkbs.2019.22.2.45
Abstract
- Allogenic keratinocyte application is widely used for treatment of second degree burns. However, there is no significant body of report on application of allogenic keratinocyte to third degree burns. A geriatric patient visited our burn center showing second to third-degree burn on dorsum of her left hand. Considering the surface area and wound depth, surgery was indicated but her medical condition and age made the surgery high risk for a long operation. Therefore, chemical escharolysis, serial bedside debridement, and cultured allogenic keratinocyte (Kaloderm®, Tegoscience, Seoul, Korea) application was done. The wound was completely epithelialized after four rounds of Kaloderm® application. For third-degree burns where definitive surgical reconstruction is precluded due to medical comorbidity of the patient, we investigated the possibility of allogenic keratinocyte treatment which may allow to avoid high-risk anesthesia and surgery.
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