Maxillofac Plast Reconstr Surg.  2019 ;41(1):15. 10.1186/s40902-019-0198-0.

Proper management of suspicious actinic cheilitis

Affiliations
  • 1Oral and Maxillofacial Microvascular Reconstruction LAB, Brong Ahafo Regional Hospital, Sunyani, Ghana. smin5@snu.ac.kr, smin_kim@msn.com.
  • 2Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul, 110-768 South Korea.
  • 3Department of Oral Pathology, College of Dentistry, Gangneung-Wonju National University, Gangneung, South Korea.

Abstract

BACKGROUND
Actinic cheilitis (AC) is a variant of actinic keratosis which is known to be a premalignant condition that could develop into squamous cell carcinoma (SCC). Epimyoepithelial carcinoma (EC) is a very rare salivary gland (SG) neoplasm that has classical biphasic histologic findings of small tubules and glandular lumina surrounded by clear myoepithelial cells.
CASE PRESENTATION
We report a very rare case of AC occurring on the lower lip of a 70-year-old woman, which is developing to the EC later.
CONCLUSIONS
Diverse appearances of AC include edematous reddish in the acute stage and grey-whitish or dried hyperkeratotic wrinkled lesions in the chronic stage for several months or even years. Accurate treatment of AC in its initial stage could be recommended to avoid further malignant transformation; proper management of clinically suspicious AC is suggested.

Keyword

Actinic cheilitis (AC); Cytokeratin immunostaining; Epimyoepithelial carcinoma (EC); Lip cancer; Minor salivary gland (MSG)

MeSH Terms

Actins*
Aged
Carcinoma, Squamous Cell
Cheilitis*
Female
Humans
Keratosis, Actinic
Lip
Lip Neoplasms
Salivary Glands
Actins
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