Prog Med Phys.  2019 Dec;30(4):89-93. 10.14316/pmp.2019.30.4.89.

Low Magnetic Field MRI Visibility of Rubber-Based Markers

Affiliations
  • 1Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea.
  • 2Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea. smjung@snu.ac.kr
  • 3Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea.

Abstract

PURPOSE
This study aims to develop new markers based on silicone rubber and urethane rubber to enhance visibility in low magnetic field magnetic resonance (MR) imaging.
METHODS
Four types of markers were fabricated using two different base materials. Two of the markers were composed of two different types of silicone rubber: DragonSkinâ„¢ 10 MEDIUM and BodyDoubleâ„¢ SILK. The other two markers were composed of types of urethane rubber: PMCâ„¢ 780 DRY and VytaFlexâ„¢ 20. Silicone oil (KF-96 1000cs) was added to the fabricated markers. The allocated amount of oil was 20% of the weight (wt%) of each respective marker. The MR images of the markers, with and without the silicone oil, were acquired using MRIdian with a low magnetic field of 0.35 T. The signal intensities of each MR image for the markers were analyzed using ImageJ software and the visibility for each was compared.
RESULTS
The highest signal intensity was observed in VytaFlexâ„¢ 20 (279.67±3.57). Large differences in the signal intensities (e.g., 627% in relative difference between BodyDoubleâ„¢ SILK and VytaFlexâ„¢ 2 0) among the markers were observed. However, the maximum difference between the signal intensities of the markers with the silicone oil showed only a 62% relative difference between PMCâ„¢ 780 DRY and DragonSkinâ„¢ 10 MEDIUM. An increase in the signal intensity of the markers with the silicone oil was observed in all markers.
CONCLUSION
New markers were successfully fabricated. Among the markers, DragonSkinâ„¢ 10 MEDIUM with silicone oil showed the highest MR signal intensity.

Keyword

Visibility; Magnetic resonance image; Low magnetic field; Rubber-based marker

MeSH Terms

Magnetic Fields*
Magnetic Resonance Imaging*
Rubber
Silicon
Silicone Elastomers
Silicones
Silk
Urethane
Rubber
Silicon
Silicone Elastomers
Silicones
Silk
Urethane

Figure

  • Fig. 1 Fabrication method of markers using DragonSkin™ MEDIUM, BodyDouble™ SILK, PMC™ 780 DRY, and VytaFlex™ 20 (Smooth-On Inc.).

  • Fig. 2 Magnetic resonance images of markers with silicone oil (first row) and without silicone oil (second row).


Cited by  1 articles

Synthetic Computed Tomography Generation while Preserving Metallic Markers for Three-Dimensional Intracavitary Radiotherapy: Preliminary Study
Hyeongmin Jin, Seonghee Kang, Hyun-Cheol Kang, Chang Heon Choi
Prog Med Phys. 2021;32(4):172-178.    doi: 10.14316/pmp.2021.32.4.172.


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