J Korean Diabetes.  2019 Dec;20(4):205-209. 10.4093/jkd.2019.20.4.205.

Metabolic Surgery and Diabetes Mellitus: Its Effects and Side Effects

• Kim MK

• KMID: 2468006
• DOI: http://doi.org/10.4093/jkd.2019.20.4.205

Abstract

Recent studies have shown that metabolic surgery can lead to the remission of diabetes mellitus (DM) in a large portion of patients with both type 2 DM and morbid obesity. Metabolic surgery may be considered for glycemic control and weight loss in obese patients with type 2 DM. The most commonly performed bariatric surgeries are sleeve gastrectomy and Roux-en-Y gastric bypass. The effect of metabolic surgery, especially Roux-en-Y gastric bypass, is thought to be caused by mechanisms other than weight loss. Increased insulin secretion associated with altered gut hormones might play a role in this improvement. After metabolic surgery, glucose, lipids, and blood pressure are greatly improved, but not all patients with type 2 DM who undergo metabolic surgery achieve DM remission.

Keyword

Bariatric surgery; Diabetes mellitus; Korea

MeSH Terms

Bariatric Surgery*
Blood Pressure
Diabetes Mellitus*
Gastrectomy
Gastric Bypass
Glucose
Humans
Insulin
Korea
Obesity, Morbid
Weight Loss
Glucose
Insulin

Figure

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  Fig. 1 Types of bariatric surgery procedures.

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  Fig. 2 Trends in primary metabolic surgical procedures. AGB, adjustable gastric banding; RYGB, Roux-en-Y gastric bypass; SG, sleeve gastrectomy; G-plication, gastric plication; D-switch, duodenal switch; OAGB, one anastomosis gastric bypass; SGJB, sleeve gastrectomy with jejunal bypass.

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