J Clin Neurol.  2019 Oct;15(4):583-584. 10.3988/jcn.2019.15.4.583.

Continuous Positive Airway Pressure Therapy in a Patient with Pantothenate-Kinase-Associated Neurodegeneration

Affiliations
  • 1Department of Neurology, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea. koodaelim@gmail.com

Abstract

No abstract available.


MeSH Terms

Continuous Positive Airway Pressure*
Humans

Figure

  • Fig. 1 Magnetic resonance imaging and polysomnography features of the patient. T2-weighted (A) and T2* susceptibility-weighted images showing a hyperintense center with a dense hypointense rim (eye-of-tiger sign) (B). C: Baseline polysomnography image revealing recurrent episodes of obstructive sleep apnea and the lowest oxygen saturation (down to 69%). D: Complete elimination of snoring and sleep apnea was confirmed at a continuous positive airway pressure of 7 cm H2O by polysomnography. CPAP: continuous positive airway pressure, EEG: electroencephalography, EKG: electrocardiogram, EMG: electromyography, EOG: electrooculography, HR: heart rate, L: left, R: right, SaO2: peripheral oxygen saturation, TA: tibialis anterior.


Reference

1. Gregory A, Hayflick SJ. Pantothenate kinase-associated neurodegeneration. In : Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, editors. GeneReviews. Seattle: University of Washington;1993.
2. McCarty SF, Gaebler-Spira D, Harvey RL. Improvement of sleep apnea in a patient with cerebral palsy. Am J Phys Med Rehabil. 2001; 80:540–542.
Article
3. Marchese-Ragona R, Vianello A, Restivo DA, Pittoni G, Lionello M, Martini A, et al. Sleep-related adductor laryngeal dystonia causing sleep apnea: a sleep-related breathing disorder diagnosed with sleep endoscopy and treated with botulinum toxin. Laryngoscope. 2013; 123:1560–1563.
4. Koo DL, Nam H, Thomas RJ, Yun CH. Sleep disturbances as a risk factor for stroke. J Stroke. 2018; 20:12–32.
Article
5. Fantini ML, Cossu G, Molari A, Cabinio M, Uyanik O, Cilia R, et al. Sleep in genetically confirmed pantothenate kinase-associated neurodegeneration: a video-polysomnographic study. Parkinsons Dis. 2010; 2010:342834.
Article
6. Hogarth P, Kurian MA, Gregory A, Csányi B, Zagustin T, Kmiec T, et al. Consensus clinical management guideline for pantothenate kinase-associated neurodegeneration (PKAN). Mol Genet Metab. 2017; 120:278–287.
Article
Full Text Links
  • JCN
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr