J Korean Assoc Oral Maxillofac Surg.  2018 Dec;44(6):282-288. 10.5125/jkaoms.2018.44.6.282.

Clinical analysis of neck node metastasis in oral cavity cancer

Affiliations
  • 1Department of Oral and Maxillofacial Surgery, Kyungpook National University School of Dentistry, Daegu, Korea.
  • 2Department of Oral and Maxillofacial Surgery, Samsung Medical Center, Seoul, Korea. jypaeng@gmail.com

Abstract


OBJECTIVES
The purpose of this study was to evaluate the neck node metastasis pattern and related clinical factors in oral cavity cancer patients.
MATERIALS AND METHODS
In total, 76 patients (47 males, 29 females) with oral squamous cell carcinoma (OSCC) who had no previous malignancies and were not undergoing neoadjuvant concomitant chemoradiotherapy or radiotherapy were selected for analysis.
RESULTS
Occult metastases were found in 8 of 52 patients with clinically negative nodes (cN0, 15.4%). Neck node metastases were found in 17 patients (22.4%). There was a statistically significant relationship between neck node metastasis and T stage (P=0.014) and between neck node metastasis and distant metastasis (Fisher's exact test, P=0.019).
CONCLUSION
Neck node metastasis was significantly related to tumor size and distant metastasis during follow-up.

Keyword

Mouth neoplasms; Lymph nodes; Metastasis; Squamous cell carcinoma

MeSH Terms

Carcinoma, Squamous Cell
Chemoradiotherapy
Follow-Up Studies
Humans
Lymph Nodes
Male
Mouth Neoplasms
Mouth*
Neck*
Neoplasm Metastasis*
Radiotherapy

Figure

  • Fig. 1 Occult metastasis in relation to oral subsites.

  • Fig. 2 Type of neck dissection. (SOHND: supraomohyoid neck dissection, mRND: modified radical neck dissection)

  • Fig. 3 Tumor size (the American Joint Committee on Cancer [AJCC] classification32).

  • Fig. 4 Clinical staging of oral squamous cell carcinoma size.

  • Fig. 5 Histological classification of oral squamous cell carcinoma.


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