J Korean Assoc Oral Maxillofac Surg.  2019 Apr;45(2):116-120. 10.5125/jkaoms.2019.45.2.116.

Misdiagnosis of ameloblastoma in a patient with clear cell odontogenic carcinoma: a case report

Affiliations
  • 1Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan, Korea. kuksjs@pusan.ac.kr
  • 2Department of Oral Pathology, BK21 Plus Project, School of Dentistry, Pusan National University, Yangsan, Korea.

Abstract

Clear cell odontogenic carcinoma (CCOC), a rare tumor in the head and neck region, displays comparable properties with other tumors clinically and pathologically. In consequence, an incorrect diagnosis may be established. A 51-year-old male patient who was admitted to the Department of Oral and Maxillofacial Surgery at Pusan National University Dental Hospital was initially diagnosed with ameloblastoma via incisional biopsy. However, the excised mass of the patient was observed to manifest histopathological characteristics of ameloblastic carcinoma. The lesion was ultimately diagnosed as clear cell odontogenic carcinoma by the Department of Oral Pathology of Pusan National Dental University. Therefore, segmental mandibulectomy and bilateral neck dissection were performed, followed by reconstruction with fibula free flap and reconstruction plate. Concomitant chemotherapy radiotherapy was not necessary. The patient has been followed up, and no recurrence has occurred 6 months after surgery.

Keyword

Neoplasms; Ameloblastoma; Clear cell odontogenic carcinoma

MeSH Terms

Ameloblastoma*
Ameloblasts
Biopsy
Busan
Diagnosis
Diagnostic Errors*
Drug Therapy
Fibula
Free Tissue Flaps
Head
Humans
Male
Mandibular Osteotomy
Middle Aged
Neck
Neck Dissection
Pathology, Oral
Radiotherapy
Recurrence
Surgery, Oral
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