Korean J Radiol.  2016 Dec;17(6):961-964. 10.3348/kjr.2016.17.6.961.

Computed Tomography Findings of Community-Acquired Stenotrophomonas Maltophilia Pneumonia in an Immunocompetent Patient: A Case Report

Affiliations
  • 1Department of Radiology, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang 10326, Korea. jeungkim@dumc.or.kr
  • 2Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang 10326, Korea.

Abstract

Stenotrophomonas maltophilia (S. maltophilia) is a rare, but globally emerging gram-negative multiple-drug-resistant organism usually found in a nosocomial setting in immunocompromised patients. To our best knowledge, computed tomography (CT) features of community-acquired S. maltophilia pneumonia have not been previously reported in an immunocompetent patient. Herein, we presented the CT findings of a previous healthy 56-year-old male with S. maltophilia pneumonia.

Keyword

Stenotrophomonas maltophilia; Community-acquired pneumonia; Immunocompetent host; CT

MeSH Terms

Anti-Bacterial Agents/therapeutic use
Bronchoalveolar Lavage Fluid/microbiology
Bronchoscopy
Gram-Negative Bacterial Infections/*diagnosis/drug therapy/microbiology
Humans
Immunocompromised Host
Levofloxacin/therapeutic use
Male
Middle Aged
Pleural Effusion/etiology
Pneumonia/*diagnosis/microbiology
Stenotrophomonas maltophilia/*isolation & purification
Tomography, X-Ray Computed
Anti-Bacterial Agents
Levofloxacin

Figure

  • Fig. 1 56-year-old man presented with 4-day history of febrile sensation. A. Initial chest radiograph shows increased interstitial markings in both lungs. B. Chest CT with lung window setting shows diffuse thickening of interlobular septae and ill-defined small nodules (arrowheads) in both upper lobes. C. In lower lung zones, CT scan shows diffuse smooth thickening of interlobular septae and patchy ground-glass opacities (arrows). D. On coronal scan, ill-defined small nodules (arrowheads) are predominantly seen in upper lung zones. E. Mediastinal window CT image shows small bilateral pleural effusion (arrowheads), pericardial effusion (white arrows), and thickening of peribronchovascular bundles. F. Follow-up chest radiograph shows ill-defined ground glass opacities in both parahilar areas and increased interstitial markings with developing bilateral pleural effusion.


Reference

1. Brooke JS. Stenotrophomonas maltophilia: an emerging global opportunistic pathogen. Clin Microbiol Rev. 2012; 25:2–41.
2. Falagas ME, Kastoris AC, Vouloumanou EK, Dimopoulos G. Community-acquired Stenotrophomonas maltophilia infections: a systematic review. Eur J Clin Microbiol Infect Dis. 2009; 28:719–730.
3. Lai CH, Chi CY, Chen HP, Chen TL, Lai CJ, Fung CP, et al. Clinical characteristics and prognostic factors of patients with Stenotrophomonas maltophilia bacteremia. J Microbiol Immunol Infect. 2004; 37:350–358.
4. Jang TN, Wang FD, Wang LS, Liu CY, Liu IM. Xanthomonas maltophilia bacteremia: an analysis of 32 cases. J Formos Med Assoc. 1992; 91:1170–1176.
5. Victor MA, Arpi M, Bruun B, Jønsson V, Hansen MM. Xanthomonas maltophilia bacteremia in immunocompromised hematological patients. Scand J Infect Dis. 1994; 26:163–170.
6. Denton M, Todd NJ, Littlewood JM. Role of anti-pseudomonal antibiotics in the emergence of Stenotrophomonas maltophilia in cystic fibrosis patients. Eur J Clin Microbiol Infect Dis. 1996; 15:402–405.
7. Burns JL, Emerson J, Stapp JR, Yim DL, Krzewinski J, Louden L, et al. Microbiology of sputum from patients at cystic fibrosis centers in the United States. Clin Infect Dis. 1998; 27:158–163.
8. Goss CH, Otto K, Aitken ML, Rubenfeld GD. Detecting Stenotrophomonas maltophilia does not reduce survival of patients with cystic fibrosis. Am J Respir Crit Care Med. 2002; 166:356–361.
9. Sakhnini E, Weissmann A, Oren I. Fulminant Stenotrophomonas maltophilia soft tissue infection in immunocompromised patients: an outbreak transmitted via tap water. Am J Med Sci. 2002; 323:269–272.
10. Denton M, Todd NJ, Kerr KG, Hawkey PM, Littlewood JM. Molecular epidemiology of Stenotrophomonas maltophilia isolated from clinical specimens from patients with cystic fibrosis and associated environmental samples. J Clin Microbiol. 1998; 36:1953–1958.
11. Gasparetto EL, Bertholdo DB, Davaus T, Marchiori E, Escuissato DL. Stenotrophomonas maltophilia pneumonia after bone marrow transplantation: case report with emphasis on the high-resolution CT findings. Br J Radiol. 2007; 80:e19–e20.
12. Kassel TW, Ryan LK, Li A. Computed tomography features of Stenotrophomonas maltophilia pneumonia in patients with neutropenic fever: report of two cases. Multidiscip Respir Med. 2013; 8:14.
Full Text Links
  • KJR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr