J Endocr Surg.  2019 Dec;19(4):157-158. 10.16956/jes.2019.19.4.157.

Preoperative Treatment with Lugol Solution for Graves' Disease

Affiliations
  • 1Division of Endocrine Surgery, Department of General Surgery, Ege University Hospital, Izmir, Turkey. ozer.makay@ege.edu.tr
  • 2Division of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, China Japan Union Hospital of Jilin University, Changchun, China.
  • 3Division for Endocrine and Minimally Invasive Surgery, Department of Human Pathology in Adulthood and Childhood “G. Barresi”, University Hospital G. Martino, University of Messina, Messina, Italy.
  • 4Department of Human Pathology in Adulthood and Childhood “G. Barresi”, University Hospital G. Martino, University of Messina, Messina, Italy.

Abstract

Graves' disease is one of the commonest causes of hyperthyroidism. Pre-treatment with Lugol solution, containing iodine/potassium iodide, to induce euthyroidism before surgery may be suggested, especially in case of adverse events due to antithyroid medication. Whether post-operative outcomes are any different following a course of Lugol solution in patient with Graves' disease is not well-documented in the literature. It is definite that large, prospective, randomized controlled trials of clinical and scientific are warranted to answer whether or not preparation with Lugol solution is necessary prior to surgery for Graves' disease.

Keyword

Graves's disease; Thyroidectomy; Lugol solution

MeSH Terms

Graves Disease*
Humans
Hyperthyroidism
Prospective Studies
Thyroidectomy

Reference

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