J Vet Sci.  2019 Sep;20(5):e46. 10.4142/jvs.2019.20.e46.

Salivary alpha-amylase as a stress biomarker in diseased dogs

Affiliations
  • 1Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea. kwseo@cnu.ac.kr
  • 2BioMedIT Group, Electronics and Telecommunications Research Institute, Daejeon 34129, Korea. junkim@etri.re.kr

Abstract

Salivary alpha-amylase (sAA) is a stress biomarker in human diseases, but there are no reports of sAA measurements in diseased dogs. This study measured the sAA and serum alpha-amylase (AA) levels in 16 healthy dogs and 31 diseased dogs using a kinetic enzyme assay to assess the stress status. The sAA and serum AA levels were significantly higher in the diseased dogs than in healthy dogs (p < 0.05), but there was no correlation between the 2 groups (r = 0.251, p = 0.089). This suggests that sAA can be useful as a stress biomarker in diseased dogs.

Keyword

Alpha-amylase; dogs; saliva; serum; stress

MeSH Terms

alpha-Amylases*
Animals
Dogs*
Enzyme Assays
Humans
Saliva
alpha-Amylases

Figure

  • Fig. 1. Relationship between the sAA and serum AA in all dogs. No correlation was observed between the alpha-amylase activities of the serum and saliva according to Spearman correlation analysis (r = 0.251, p = 0.089). sAA, salivary alpha-amylase; AA, alpha-amylase.


Reference

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