J Korean Orthop Assoc.  1972 Dec;7(4):481-484. 10.4055/jkoa.1972.7.4.481.

A Case of Severe Hypersensitivity Reaction to Para-Amino Salicyic Acid

• Eum JS
• Lee SY
• Ihin JC
• Kim ID

• KMID: 2463939
• DOI: http://doi.org/10.4055/jkoa.1972.7.4.481

Abstract

Hypersensitivity reactions against para-aminos alicylic have been recorded infrequently in the literature. It is the purpose of this report to emphasize the possible occurence of severe reactions which may result in death if unrecognized. The recognition of the early signs and symptoms of a hypersensitivity reaction to antituberculous drugs is all important because serious consequences can ensue from continued administration of the drug after the first sign of a reaction. This case present acute liver failure as part of a generalized hypersensititivity reaction to para-aminosalicylic acid, based on clinical findings liver function test, course and response to cortison derivatives.

MeSH Terms

Aminosalicylic Acid
Hypersensitivity*
Liver Failure, Acute
Liver Function Tests
Aminosalicylic Acid