J Korean Radiol Soc.  1982 Sep;18(3):636-646. 10.3348/jkrs.1982.18.3.636.

Clinical dosimetric planning for total body irradiation

• Lim SJ
• Kim GE
• Lee DH
• Chu SS
• Park CY

• KMID: 2463292
• DOI: http://doi.org/10.3348/jkrs.1982.18.3.636

Abstract

Widely applied total body irradiation (TBI) for bone marrow transplantation and treatment of lymphoma anddisseminated other malignancies, can be effectively performed when uniformity of dose distribution is established.Special considerations for TBI dosimetry are required as several problems associated with very large field sizeand long source-skin-distance (SSD) arose. For the TBI with LMR-13 linear accelerator, radiobiological aspects,techniques and methods were discussed and through direct phatom measurements, basic radiation physical data wereobtained. Following results are presented. 1. Adequate field size up to 130x 130cm for the whole body at 4.1m fromthe source can be provided. Though about 20% decrease of beam intensity in the corners of the field was detected,uniformity of dose distribution can be esstablished with the patient seated with flexion of the legs. 2. Lateralopposing two portals were used as the treatment geometry. 3. The bed made of styrofoam was devised for thefixation of the patient position and thick hospital gown itself acted as the bolus. 4. Compensation filters weredesigned for the uniform dose distribution and the central axis dose difference less than ±5% was achieved. 5.For the further repeated measurements, humanoid phantom in sitting position, as large as a man, was made with theuse of soft tissue equivalent paraffin compound and lung tissue equivalent cork. 6. Dosage at several anatomiclocations were monitored using TLD chips.

MeSH Terms

Bone Marrow Transplantation
Clothing
Compensation and Redress
Humans
Leg
Lung
Lymphoma
Paraffin
Particle Accelerators
Whole-Body Irradiation*
Paraffin